Dave Gower said:
I'm biased towards the Focus, which now has good quality and still gets raves from journalists for handling, ergonomics, etc (a little more expensive than the Neon however). There's also the Elantra and Protege which both get good reviews. I really recommend looking at these three before buying.
The Focus has questionable interior styling. Some like it, some don't. The price does seem to be a bit on the steep side, a used Taurus is about the exact same price, for a bigger car. It is also consistently higher priced than equally equipped Neon or Cavalier by a couple grand. I drove a Focus a couple times, handles fine. I'd take the keys if someone threw them to me. The Cavalier is boring, but cheap. The platform may be old but for basic transportation it's fine. Rumour has it the Aveo is more expensive than the Cavalier.
Newer Hyundais have surprised me, they aren't as bad as Pony or Excel. I might even say they are "good." The Accent is a smaller car but also dirt cheap.
After that there's a long list (I'm taking sedans only since the Neon isn't offered in a hatchback) : Corolla and Civic (good quality but some find overpriced and dull), Echo and Aerio (spacious but to some eyes weird looking), Kia Rio (cheap and thirsty but some like it), Jetta (pricey and due for updating). GM only has the dated Cavalier which is cheap but overdue for replacement. There's also new models coming soon to GM (Aveo) and Mazda (Mazda3, highly rated by journalists).
But it's your money.
I like the Corolla, while a little over priced and dull, I find it has good ergonomics and a nice feel. I don't like the interior of the Civic, I find it too dull and stiff.
The Jetta is too overpriced. The initial price is high, and they are a terrible car to buy used (guess what type of cars I buy?), too high resale value(if you buy new this might be good). I see some with 170 000+km for just a few thousand less than new. Personally I don't care for the interior. One reviewer said there were "Three strange knobs, possibly used for HVAC" although the HVAC controls are very straight forward, but anyhow.
Another car not mentioned is Sentra. I think it's too boring.
In the end I'm sure any of these cars would be fine. This is just my opinion, you idea of good ergonomics might be different. I drive a Neon, I like it. Again I'd be willing to drive almost anything.